Nasal Nitric Oxide (nNO) measurement is a specialized test used primarily to investigate the function of the nasal epithelium and cilia.
What is nNO:
nNO measures the levels of nitric oxide in the nasal cavity. Low values are associated with impaired mucociliary clearance.
When is it needed:
The test is indicated primarily for:
- suspected Primary Ciliary Dyskinesia (PCD)
- chronic or recurrent rhinosinusitis
- chronic productive cough from an early age
- investigation of unexplained respiratory infections.
How it is performed:
The measurement is carried out using specialized equipment, either through a breathing maneuver or passive airflow from the nasal cavity. It is painless and takes only a few minutes.
Why it is important:
nNO is a valuable screening tool for rare diseases and helps facilitate timely referral for further specialized evaluation.
